How can we promote health? In the midst of the century we find ourselves struggling to fight a global epidemic in health: chronic disease. Chronic disease is preventable and human induced, treatment regimes must be re-evaluated. This Keystone presentation aims to provide education for prevention and treatment of chronic disease. I highlight functional medicine, which is a systems-biology based approach geared towards finding the root cause of a disease to heal sustainably and encourage longevity. Understanding the relationship between mind, body, gut, and food provides a foundation for making conscious health decisions and reducing incidence of chronic disease.