Liam Johnston
Disrupting the Genome to Treat its Instability: The Role of CRISPR-Cas9 in Cancer Therapy
Mentor: Dr. Marina Tourlakis
| What’s the first thing that comes to mind when you think of gene editing? GMOs or designer babies, perhaps? What about cancer? The field of cancer therapy sits at a crossroads with some highly curable forms, such as Hodgkin’s Lymphoma, and some nearly untreatable forms, such as ovarian cancer. Given the rise of the CRISPR-Cas9 gene editing tool, I ask “How can the application of genetics improve cancer treatment?” Through a rigorous analysis of the biochemistry and molecular mechanisms of gene editing, I present here a primer on CRISPR-Cas9 and its potential application as a cancer therapy. |
