Bria Mele ‘16

Master’s Student, Community Health Sciences at the University of Calgary

Bria’s Question: What is the biological basis of choice?

Keystone Title: A Path Towards Pathos: A Genetic Approach to Understanding Apathy and Decision-Making Deficits in Parkinson’s Disease

Abstract: Bria’s keystone investigates apathy in Parkinson’s Disease and gives particular consideration to the role of dopamine levels, which have been under-examined in existing research. Parkinson’s Disease is commonly represented as a movement disorder, but it also presents with several non-motor symptoms including neuropsychiatric symptoms. Mele presents a literature review of the research on both areas of symptoms and then proposes research specifically on apathy as it presents in Parkinson’s Disease, the least understood non-motor symptom of PD.

Which Concentration Courses did you take?

  • Behavioural Economics
  • Brain Disorders
  • Drugs and Behaviours
  • Mechanisms of Neuropathology
  • Brain Plasticity and Memory Cognition
  • Molecular Biology

Which Electives did you take?

  • Public Health Policy
  • Politics of Health in South Africa
  • Statistics
  • Discrete Mathematics
  • Quantitative Research Methods
  • Microeconomics
  • Spanish I

What did you do for Experiential Learning?
I interned at Alberta Health Services. My objective was to understand the research scope of projects that are focused on geriatrics—specifically, neurodegenerative diseases that onset in old age.

Quest University Canada is suspending regular academic programming following
completion of the current academic year in April 2023.

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